Toxicology in the 21st century and OMICS approaches Sep. 16 2024
Major goals with tox21 approaches
- Provide broader coverage of chemicals, mixtures
- Broader coverage of doses, endpoints and life-stage vulnerabilities
- Reduce cost and time of testing, increase efficiency, reach decision quickly
- Implement 3R principles
- Predictive and reproducible models
- Encourage of integration of mechanistic toxicologic data with population-based data for regulatory purposes