Individual drug metabolism Sep. 10 2024

1. SNP: Single nucleotide polymorphism or Single nucleotide variation (SNV).
2. MR: Drug/Metabolite

Points

1. Important drug-drug interaction on enzyme and transporter level
2. Identification of function and polymorphism in drug transporters
3. Characterize the interplay between transporters and metabolising enzymes
4. Individualized therapy with pharmacogenetic biomarkers for prediction of drug response and toxicity yields more efficient and safer drug therapy
5. Explore variability assays for the HLA locus for prediction of immune mediated reactions
6. The missing hereditability