Cell death in Toxicology Sep. 10 2024

1. Initial caspase cleave each other at first, and then cleave effective caspase.

Points

1. Briefly describe the difference between main cell death types, such as apoptosis, necrosis, autophagy, senescense and pyroptosis.

2. Describe the extrinsic and the extrinsic apoptotic pathways?

3. Be aware of the association between various cell death modes and activation of the innate immune system.

4. What may occur in an organism in situations of excess and inhibited apoptosis, respectively?

5. What is the danger theory and how does it relate to cell death?